Single gal and comedian Chelsea Handler, 35 will host this year’s MTV’s Video Music Awards live from Los Angeles  on September 12.

The raunchy Handler replaces British comic star Russell Brand, who has hosted the show for the past two seasons.  Kanye West, will also perform at the show for the first time since he infamously interrupted Taylor Swift onstage.

Other big performers of the night: Justin Bieber, Ne-Yo, Trey Songz, Nicki Minaj and Selena Gomez.

Will Chelsea make a good host?